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Termination can occur when a
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G-C hairpin loop in the growing
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transcript is followed by a run of
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U's. The hairpin causes a
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pause in transcription, and the
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poly-U sequence causes loose
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binding of the RNAP. The
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precise terminus is not
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important because the correct
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stopping point for translation is
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determined by the first stop
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codon.
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