| PROTEOMICS |
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| alternative splicing (2-3/gene) and multiple different types of |
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| post-translational modification, each of which may go to |
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| differing degrees of completion, make the proteome |
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| MUCH larger than the transcriptome (10X-100X) |
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| protein levels and transcript expression not perfectly |
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| correlated |
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| our ability to predict genes and transcripts, let alone proteins, |
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| from primary genomic sequence is only fair. |
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| proteome informatics problems: |
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| a. protein identification |
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| b. pattern analysis--similar
to array analysis |
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