Where are SNP's from?
100 new polymorphisms per individual--most
destined to die out or remain rare
most present-day SNP's arise from a period after
speciation but before different human populations
emerged, with about 85% present in all major
human populations
founder population size approx 10,000 with 5,000
generations since then; survival probability about
0.005 if a SNP present in one copy at t = 0; most
SNP's arose at t < 0.