What the biostatistician needs to know about molecular biology
#8

Format of these lectures

Outline--comparative genomics

Terminology

BLAST--protein or DNA homology

PSI-BLAST

Motif finding--statistical methods

Motif finding--exhaustive methods

Motif finding--the future

Synteny

Matching orthologous genes (Batzoglu)

Slide 12

Prokaryotic comparative genomics

Prokaryotes (2)

Prokaryotes (3)

Eukaryotic comparative genomics

What is required for multicellular life?

Fly-worm-yeast

What is the relationship between the zebrafish and human genomes?

Slide 20

Slide 21

Using comparative genomics to locate TF sites

Slide 23

TF binding sites (cont.)

This ends the talk on comparative genomics. This ends talk on company genomics.
The sand's the take on accompanying gnomes.
Send the toast--the gnomes are coming.