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only 19% of noncoding sequence has >50%
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probability of being aligned, but this 19% contains
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74/75 of the muscle-specific sites and 75% of the
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Sp1 binding sites
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if the Gibbs sampler looks for motifs in the 19% of
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conserved sequence, the three principal motifs are
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found
easily
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conclusion: comparative genomics may be a fruitful
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approach to detection of regulatory sites in DNA
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