Biostat 580B - Statistical Genetics Seminar

Autumn Quarter 2006
Tuesday 4:00-5:00, F643 HSB

CURRENT SCHEDULE

October 3
Organizational meeting. ASHG poster presentations by Amy Anderson and Weiva Sieh.

October 10
Elisabeth Rosenthal and Tanya Granston.
Background to case-control tests and why population structure is of concern.
Risch NJ. 2000. Searching for genetic determinants in the new millenium. Nature 405:847-856.
Knowler WC, et al. 1989. Gm3;5,13,14 and type 2 diabetes mellitus: An association in American Indians with genetic admixture. Am J Hum Genet 43:520-526.
Lander ES, Schork NJ. 1994. Genetic dissection of complex traits. Science 265:2037-2048.

October 17
Carolyn Hutter and Joan Zhao.
Voight BJ, Pritchard JK. 2005. Confounding from cryptic relatedness in case-control association studies. PLoS Genetics 1(3):e32.

October 24
Audrey Fu and Takumi Saegusa
Eden R. Martin, Stephanie A. Monks, Liling L. Warren, and Norman L. Kaplan (2000) A test for linkage and association in general pedigrees: the pedigree disequilibrium test. AJHG. 67 146-154
Spielman RS, McGinnis RE and Ewens WJ (1993) Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). AJHG. 52 506-516

October 31
Yoonha Choi and Daryl Morris
Yu et al. 2006. A Unified Mixed-Model Method for Association Mapping that Accounts for Multiple Levels of Relatedness. Nature Genetics 38:203-208.

November 7
Yanming Di and Maggie Andrilla
Visscher et al. 2006. Assumption-Free Estimation of Heritability from Genome-Wide Identity-by-Descent Sharing between Full Siblings. PLoS Genetics 2:316-325.

November 14
Dustin Weems, Pui Yee Fong and Amy Laird
Hinds et al. 2006. Common Deletions and SNPs are in Linkage Disequilibrium in the Human Genome. Nature Genetics 38:82-85.
Locke et al. 2006. Linkage Disequilibrium and Heritability of Copy-Number Polymorphisms within Duplicated Regions of the Human Genome. Am J Hum Genet 79:275-290

November 21
Liping Tong, Peter Chi and Sangsson Woo
Evans et al. 2006. Two-Stage Two-Locus Models in Genome-Wide Association. PLoS Genetics 2:1424-1432.

November 28
Grace Ge, Joshua Sampson and Heidi Tan
Bieber et al. 2006. Human Genetics: Finding Criminals through DNA of their Relatives. Science 312:1315-1316 (plus online supporting material).

December 5
Charla Lambert and Diana Fisher
Terwilliger and Hiekkalinna. 2006. An Utter Refutation of the 'Fundamental Theorem of the HapMap.' European J Human Genetics 14:426-437.