Biostat 580B - Statistical Genetics Seminar

Fall Quarter 2005
Seminar: Tuesday 4:00-5:00, in F643 HSB

CURRENT SCHEDULE

Oct. 4 Organizational meeting. Bring, written down on a piece of paper, general topic(s) you would be interested in reading about that are pertinent to the broad field of statistical genetics. If you have any specific articles from the literature to suggest, write those down as well. We will (as usual) pick one or more areas for literature review, for weeks in which we do not have a research presentation, and we will set up the rest of the quarter's schedule.

Oct. 11 Yun Ju Sung: Research Presentation: "Linkage analysis for two loci plus a polygenic component"

Oct. 18 We will use this day for practice talks and to give feedback on draft posters for people who will be attending the IGES and/or ASHG meetings. The people that I am aware will be presenting at these meetings are: Liping Tong, Bill Stewart, Adele Mitchell, Elisabeth Rosenthal, Garrett Hellenthal, Bertrand Servin, Paul Scheet, and Yun Ju Sung. Liping has a talk; the others have posters, so I would suggest that the first 15 minutes Liping can give her talk, and the rest of the hour people can circulate and provide feedback on posters. Maybe we can split the second half of the hour into two parts, with so many people having posters.

Oct. 25 Arindam Choudhury, Audrey Fu:

• Mirea, Bull & Stafford (2003) "Comparison of Haseman-Elston regression analyses using single, summary, and logitudinal measures of systolic blood presure." BMC Genetics 4(Supl 1):S23.
• Also, as a reference: Elston R et al (2000) "Haseman-Elston revisited". Genet. Epidemiol. 19:1-17

Nov. 1 Joe Rothstein, Liping Tong

• Gauderman & Siegmund (2001) Gene-Environment Interaction and affected sib pair linkage analysis. Human Heredity 52:34-46.

Nov. 8 Garrett Hellenthal, Eric Rynes

• Schouten et al (2005) The impact of using related individuals for haplotype reconstruction in population studies. Genetics, November issue. IMPORTANT: epub date: June 8, 2005 (look in the "published articles ahead of print section towards the end). I found it with the "search" button under the Highwire link to Genetics, with the first author as the search criterion. Some people are reporting trouble finding the paper; try again since Nov. 4 the advance pub site was updated.

Nov. 15 Bill Stewart, Paul Scheet

• Reich et al (2005) Whole genome admixture scan for M.S. susceptibility" Nature Genetics 37:1113

Nov. 22 Adele Mitchell, Yoonha Choi

• G Abecasis and J Wigginton (2005) Handling marker-marker linkage disequilibrium: Pedigree analysis with clustered markers. Am J Hum Genet 77:754-767.

Nov. 29 Weiva Sieh, Bertrand Servin

• M Li, M Boehnke, GR Abecasis (2005) Joint modeling of linkage and association: identifying SNPs responsible for a linkage signal. Am J Hum Genet 76:934-949.

Dec. 6 Grace Ge, Elisabeth Rosenthal

• Nothnagel and Rohde (2004) The effect of single-nucleotide polymorphism marker selection on patterns of haplotype blocks and haplotype frequency estimates. Am J Hum Genet 77:988-998.