March 30: Research talk by Yunju Sung titled "Ascertainment Correction for Variance Components of Multivariate Quantitative Autism Traits." I'll be at the ENAR meeting that day; however, please bring a proposed topic for the quarter on a piece of paper. I've asked Angel Wan to collect them and deliver them to me.
April 6: The first half will be organizational. Check out the proposed new topics list . The second half will be a discussion of: "Are We There Yet?": Deciding When One Has Demonstrated Specific Genetic Causation in Complex Diseases and Quantitative Traits Am. J. Hum. Genet., 73:711-719, 2003 which will be led by Ying Huang and Caroline Cutting.
April 13: Monty Slatkin is visiting and will be giving the statistical genetics seminar: "A Population-Genetic Test of Founder Effects and Implications for Ashkenazi Jewish Diseases." For those interested, check out the following related paper: Risch N, Tang H, Katzenstein H, Ekstein J. Geographic distribution of disease mutations in the Ashkenazi Jewish population supports genetic drift over selection. Am J Hum Genet. 2003 Apr;72(4):812-22.
April 20: Rob Igo and Garrett Hellenthal will be discussing: Mark A. Beaumont, Bruce Rannala (2004) The Bayesian revolution in genetics. Nat Rev Genet 5:251-261
April 27: Audrey Fu and Ting-Yuan Liu will discuss the methods paper relevant to the May 4 topic: Kuhner MK, Yamato J, Felsenstein J (1995) Estimating effective population size and mutation rate from sequence data using Metropolis-Hastings sampling. Genetics. 140(4):1421-30
May 4: Mary Kuhner will be visiting to present her paper: Kuhner MK, Beerli P, Yamato J, Felsenstein J (2000) Usefulness of single nucleotide polymorphism data for estimating population parameters. Genetics. 156(1):439-47
May 11: Joe Rothstein and Angel Wan will be discussing: Dana C. Crawford, Christopher S. Carlson, Mark J. Rieder, Dana P. Carrington, Qian Yi, Joshua D. Smith, Michael A. Eberle, Leonid Kruglyak, and Deborah A. Nickerson (2004) Haplotype Diversity across 100 Candidate Genes for Inflammation, Lipid Metabolism, and Blood Pressure Regulation in Two Populations. Am J Hum Genet 74:610-622
May 18: Elisabeth Rosenthal will be talking about her dissertation work: "Linkage and Segregation Analysis Allowing for Multiallelic Inheritance"
May 25: Arindam Roy Choudhury and Saonli Basu will be discussing: Rat Genome Sequencing Project Consortium (2004) Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature 428:493-521
June 1: Paul Scheet will be talking about some of his recent work: "From GERBIL to HAMSTER: a new model for haplotype variation"