Biostat 580B - Statistical Genetics Seminar

Spring Quarter 2007
Seminar: Tuesday 4:00-5:00, probably in F643 HSB

CURRENT SCHEDULE

Mar. 27: We will have the usual organizational meeting to pick topics and speakers. Bring one or more topic or paper written down on a piece of paper.

Apr. 3: Yanming Di
Zollner and Pritchard (2007) Overcoming the Winner's Curse: Estimating Penetrance Parameters from Case-Control Data. Am J Hum Genet 80:605-615

Apr. 10: Pui Yee Fong and Sangsoon Woo
Harald H. H. Göring, Joseph D. Terwilliger, and John Blangero (2001) Large Upward Bias in Estimation of Locus-Specific Effects from Genomewide Scans Am J Hum Genet 69:1357-1369

Apr. 17: Amy Anderson and Carra Carty
Gil McVean (2007) The structure of linkage disequilibrium around a selective sweep. Genetics 175:1395-1406

Apr. 24: Ben Ely and Carolyn Hutter
Main paper: Zaykin DV, Meng ZL, Ehm MG (2006) Contrasting linkage-disequilibrium patterns between cases and controls as a novel association-mapping method. Am J Hum Genet 78:737-746; and
Also relevant: Wang T, Zhu X, and Elston RC (2007) Improving Power in contrasting Linkage Disequilibrium patterns between cases and controls. Am J Hum Genet May 80(5) Epub March 28, 2007.

May 1: Liping Tong and Rori Rohlfs
Smith TF and Waterman MS (1981) Identification of common molecular subsequences. J Mol Biol 147:195-197.
Get a copy of the paper from Waterman's web site: www.cmb.usc.edu/people/msw/publications.html

May 8: Grace Ge
Research talk: "Exploring the genetics of time-varying Quantitative Trait from longitudinal data--QTL mapping for a complex trait".

May 16: Elisabeth Rosenthal & Yoonha Choi
Price TS et al (2005) SW-ARRAY: a dynamic programming solution for the identification of copy-number changes in genomic DNA using array comparative genome hybridization data. Nucleic Acids Research 33:3455-3464.
Bansal V et al (2007) Evidence for large inversion polymorphisms in the human genome from HapMap data Genome Research 17:219-230.

May 22: Weiva Sieh: Research talk
Challenges in mapping disease genes: Alzheimer's disease and ALS/PDC of Guam

May 29: Audrey Fu: Research talk
Incorporating linkage disequilibrium into sib pair studies using dense SNP data.