Biostat 580B - Statistical Genetics Seminar

Instructor: Ellen Wijsman
Instructor: Elizabeth Thompson

1 credit

Winter Quarter 2000
Seminar: Tuesday 4:00-5:00 F-600 Biostatistics conference room

WINTER 2000 SCHEDULE

We continue the 3 themes chosen fall quarter: (1) Human population genetics esp. with reference to use of haplotype data; (2) Linkage analysis from 1934-1999, including modelling, heterogeneity, choice of prior distributions, and possibly motivating with a case-study (that worked); (3) recent literature (the past 2 years) including gene expression chips, gene-environment interactions, etc.

Jan. 4:

Ellen Wijsman - Genetics of dyslexia

Jan 11:

Cancelled - no meeting

Jan 18:

Nicky Chapman:
PM McKeigue (1998) Mapping genes that underlie ethnic differences in disease risk: methods for detecting linkage in admixed populations, bu conditioning on parental admixture. Am J Hum Genet 63(1):241-251 (July issue). You can get get this through the electronic journal web site at the UW.

Jan 25:

Matthew Stephens - Oxford University
Matthew will present some of his recent research work with Jonathan Pritchard and Peter Donnelly on association mapping in structured populations.
Note that Matthew is a candidate for the Statistical Genetics faculty position in Statistics, and that he will give the Statistics Dept seminar on Jan 24 (3.30 p.m., Smith 205), on some new importance sampling and MCMC methods for inference of evolutionary and demographic parameters.

Feb. 1:

Lindsey Dubb:
CI AMos (1994) Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet 54:535-543. (Copies of the paper are in the biostat and stat statgen boxes).

Feb. 8:

Warwick Daw:

Williams et al (1999) Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. I. Likelihood formulation and simulation results. Am J Hum Genet 65:1134-1147 (Oct. issue), and

Williams et al (1999) Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials. Am J Hum Genet 65:1148-1160 (Oct issue).

You can get get these through the electronic journal web site at the UW.

Feb. 15

France Gagnon:

SM Leal and J Ott (2000) Effects of stratification in the analysis of affected-sib-pair data: benefits and costs. Am J Hum Genet 66:000-000 (it is in the Feb 2000 issue, latest issue, which you can get to through the electronic journal web site at the UW.

Feb 22:

Do Peterson: Will give a summary of his current research: "On the way to distribution theory for the recurrence risk ratio"

Anne_louise Leutenegger: Will give a summary of her current research: "Identification of candidate regions for homozygosity mapping using pairs of markers"

Feb 29:

Erin Conlon and Maureen Reiner:

DM Umbrach and CR Weinberg (2000) The use of case-parent tirads to study joint effects of genotype and exposure. Am J Hum Genet 66:251-261 (Jan). You can get this through the electronic journal web site at the UW.

Mar 7:

Stephanie Monks:

E Strauss (1999) mtDNA Shows Signs of Paternal Influence. Science Dec 24 1999: 2436

P Awadalla, A Eyre-Walker, and JM Smith (1999) Linkage Disequilibrium and Recombination in Hominid Mitochondrial DNA. Science Dec 24 1999: 2524-2525

You can get these through the electronic journal web site at the UW.

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