Topics suggested Fall 2004

One overarching approach that people are suggesting is to look at some real studies, both human and non-human. It would be useful for each topic area to make sure we include one or more such real study.


Topic group 1:

Association studies

Introducing LD into linkage analysis

Methods using haplotypes, update on and perspectives for the HapMap project, TagSNPs, etc.

Haplotype estimation/reconstruction

Recombination hot spot detection


Topic group 2:

Trait models

Maybe some quantitative genetics.


Topic group 3:

Mapping functions

Modelling IBD processes

Review current ideas for mapping genes involved in complex traits

Measures of information in gene mapping

Problems, errors about genetical data


Topic group 4

Phylogeography

Natural selection with coalescent (Neuhauser)

Coalescent model

Using the coalescent to do gene mapping


Topic group 5:

Reproducibility of genetic tests (sensitivity, specificity, predictive value)


Specific papers: