| Multiple Sequence Alignment |
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| • | ClustalW |
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| – | Global multiple
alignment |
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| – | Each pair of
sequences is compared over their |
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| entire length
with gaps introduced to obtain the |
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| optimal alignment
(using one set of parameters) |
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| – | Sequences are
grouped into clusters on the basis |
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| of similarity |
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| – | The two most
similar sequences are aligned, and |
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| additional
sequences are added to this alignment |
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| one at time
(using different parameters based on |
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| extent of
similarity) |
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