BIOEN 455 Homepage

BIOEN 455 homepage

When? Winter 2017, WF 2:00-3:20 PM (lectures) and M 12:30 PM-3:20 PM (labs)

Where? The lectures will be in Loew Hall 111. The labs will be in the Foege building’s Advanced Computing Lab (N140) and in the Folch Lab (Foege N423C).

Assignments and Grading: Team-based presentations. Class participation can increase your grade by as much as 0.1 points (over 4).

Handouts: must be downloaded by student.

Recommended Textbook: “Introduction to BioMEMS” (Albert Folch, CRC Press). Three e-book copies are available from the UW Libraries. The cheapest way to obtain the printed book is through Amazon Marketplace here, (oscillates around $60), but the ebook / rental versions can be found for as little as $26. The publisher has allowed me to offer (only to UW students) free PDFs of the uncorrected drafts of the textbook (see “textbook chapters” in the table below), but they have editing errors.

Disclaimer: I’m not recommending this book to make money with my students. I reimburse the royalties back to my students. I spent 5 years writing it because there was no book that covered the field with the appropriate breadth of scope, and still there is no other one. Since it came out in mid-2013, it has been adopted by more than 70 universities in 15 countries.

Important note for disabled individuals: If you would like to request academic accommodations due to a disability, please contact Disabled Student Services, 448 Schmitz, (206) 543-8924 (V/TTY). If you have a letter from Disabled Student Services indicating you have a disability that requires academic accommodations, please present the letter to me so we can discuss the accommodations you might need for the class.

Note that weeks and sections do not necessarily correspond exactly

Week / Section	Lecture (by section)	Handouts (PDF) (by section)		Lab (approx. schedule)
0	It's a small world Dimensions and scaling challenges involved in going from macro to micro to nano	Section 0	Teaching Appendix	Jan 9
1	How do we make small things? Introduction to micropatterning, micromachining, and micromolding with an emphasis on biomaterials restrictions	Section 1 slides or textbook Chapter 1	Section 1 appendix on 3D printing	NO LAB Mon Jan 18 (MLK Holiday)
2	Micropatterning of substrates and cells Self-assembled monolayers, chemically-bound biomolecules, biocompatible/biodegradable polymers	Section 2 slides or textbook Chapter 2		Jan 23
3	Microfluidics Introduction to microfluidics, properties of biological fluids in microchannels, mathematical modeling of fluid flow	Section 3 slides or textbook Chapter 3		Jan 30
4	Molecular biology on a chip Chromatographic separations on a chip, DNA prisms, deterministic lateral displacement, isoelectric focusing, free-flow electrophoresis, mass spectrometry, PCR chips	Section 4 slides or textbook Chapter 4		Feb 6
5	Cell-based chips for biotechnology Miniature enzymatic assays, DNA microarrays, optical detection methods amenable to miniaturization	Section 5 slides or textbook Chapter 5		Feb 13
6	BioMEMS for cell biology Enabling the control of cell-substrate, cell-cell, and cell-medium interactions	Section 6 slides or textbook Chapter 6		NO LAB Mon Feb 20 (President’s Day)
7	Tissue microengineering Introduction to biomimetic substrates and microscaffolds for tissue engineering applications	Section 7 slides or textbook Chapter 7		Feb 27
8	Microfabricated implants and biosensors Implantable microelectrodes, microtweezers.	Section 8 slides or textbook Chapter 8	BioMEMS Hall of Fame	March 6