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Bioen 599 F, Autumn 2000 Bioengineering Principles of Physiology |
Lecture Material and Notes Week 3, Lecture 9: Processes
that generate chemical potential energy Lecture theme and outline: · Absolute requirement for steady state function is continuous generation of ATP. · Chemical capacitance in nerves and muscles in the form of PCr and creatine kinase; analogy with electrical capacitance as storage of energy; output of current (chemical flux) is a dissipation that reduces potential. · Metabolic systems; catabolism of carbohydrate and fats produce ATP. · Oxidative processes dominate mammalian systems; nature of oxioreduction - a bit more chemistry. · Mitochondrial oxidative phosphorylation. · Glycolylsis. · Storage forms for metabolism: glycogen and triglyceride inside cells. · Transient ability to function as a closed system. · Therefore, open systems are needed for longer term steady state function. Readings: See Lecture 8. |
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Contact the instructor at: kushmeri@u.washington.edu
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