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Bioen 599 F, Autumn 2000 Bioengineering Principles of Physiology

Lecture Material and Notes

Week 8, Lecture 22: Neural circuits are control systems: feedback, feedforward and integration
Paolo Vicini

Lecture theme and outline: Definition of control system. The control problem and its components: input (control reference); controller; the system to be controlled; a measurement device; output (the controlled variable); an objective function. Basics of control theory.

  • Feedback and feedforward control: Feedback Control is driven by the error between prediction and current state; corrections to the control are made on the basis of this difference.
  • Feedforward (model-based, indirect) Control is based on a model of the dynamics of the system, and solves for the inverse dynamics given the input.

Lessons from neural networks.

Suggested reading:

  1. Chapter 2: Coordination of catabolism and biosynthesis, p. 82-88
  2. Chapter 15: Examples of positive feedback, p. 757-758
  3. Chapter 15: The Logic of Intracellular Signaling: Lessons from Computer-based 'Neural Networks', p. 778-782

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XX/XX/XX

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