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Bioinformatics Teaching - Dr. Timothy Rose PABIO 536 - Bioinformatics and Gene Sequence Analysis PHG 581 – Genetic Services
and Bioinformatics Biological Information Resource BackgroundI came to the University of Washington in 1995 after having worked for ten
years in the biotech industry. Prior to joining the UW faculty, my research
dealt with the functional and structural aspects of related genes and gene
products. In the biotech industry, I was involved with the cloning and
characterization of a number of different growth factor and cytokine gene
families, including oncostatin M, a member of the IL-6 family of cytokines.
This work gave me a breadth of knowledge concerning the structural and
functional characteristics of a variety of medically important gene products
and their receptors. I have used this knowledge to continue to develop
strategies for the identification and characterization of related molecules
using both computer-based methods for acquisition, archival and comparison of
biological sequence information, and practical molecular biology techniques
for the identification and characterization of unknown distantly related gene
sequences. I have also been involved with the development of new
bioinformatic software over the years, including GenePro, PatMat, as well as
software for sequencing, database construction, database searching and database
archival. I have obtained funding for and maintain a "Biological Information
Resource" for the students of the University of Washington which I
use in conjunction with a bioinformatics class (PABIO/MEBI/PHG 536 -
Bioinformatics and Gene Sequence Analysis) that I developed and teach
within the Interdisciplinary Program in Pathobiology, the Department of
Biomedical Health Informatics and the Institute for Public Health Genetics.
This site which is accessed world wide, has gene sequence analysis programs
that have been developed by programmers in my lab as well as programs
developed by members of the Departments of Molecular Biotechnology and
Genetics. I have also helped to develop software based on methods we have
developed for the design of consensus-degenerate hybrid oligonucleotide PCR
primers (iCODEHOPS).
This software is made available through the Center for Public Health
Informatics at the |
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Last updated 01/15/09 T. Rose |