PABIO/ MEBI/ PHG 536 Spring Quarter 2009

http://courses.washington.edu/bioinfo/

Course Organizer:

Timothy Rose, Professor

Dept. Pediatrics, University of Washington

Center for Childhood Infections and Prematurity Research

Seattle Children’s Research Institute

(206-884-8229, trose@u.washington.edu)

 

TA:

Lucia Vojtech (206-399-6461), luciav@u.washington.edu

 

Mondays and Wednesdays 10:00-11:20

HSL Learning Commons Classroom A (Computer Lab)

 

 

Week 1

March 30

The nature of biological sequences

Introduction/Lecture

 

April 1

NCBI resources and databases

Lecture/Lab

 

April 3

HW due

 

Week 2

April 6

NCBI resources

DNA analysis

HW Discussion

Lecture/Lab

 

April 8

DNA analysis

Lab

 

April 10

HW due

 

Week 3

April 13

DNA analysis

Protein analysis

HW Discussion

Lecture/Lab

 

April 15

Protein analysis

Lab

 

April 17

HW due

 

Week 4

Apr 20

Protein analysis

BLAST searching – Nucleotide BLAST

HW Discussion

Lecture/Lab

 

April 22

Nucleotide BLAST

Lab

 

April 24

HW due

 

Week 5

Apr 27

Nucleotide BLAST

Protein BLAST

HW Discussion

Lecture/Lab

 

April 29

Protein motifs

Lecture/Lab

 

May 1

HW due

 

Week 6

May 4

Protein BLAST

EST/Gene structure

HW Discussion

Lecture/Lab

 

May 6

EST/Gene structure

Lab

 

May 8

HW due

 

Week 7

May 11

EST/Gene structure

SNP analysis

HW Discussion

Lecture/Lab

 

May 13

SNP analysis

Lecture/Lab

 

May 15

HW due

 

Week 8

May 18

SNP analysis

Multiple sequence alignment

HW Discussion

Lecture/lab

 

May 20

Phylogenetic analysis

Lecture/lab

Week 9

May 25

Memorial Day Holiday

 

 

May 27

Phylogenetic analysis

Take-home finals distributed

Lab

 

May 29

HW due

 

Week 10

June 1

Sequence alignment/phylogenetic analysis

Protein structure modeling

HW Discussion

Lecture/lab

 

June 3

Protein structure

Lab

 

June 5

HW due

 

Finals Week

June 10

Take-home finals due