Inhibitors of RANK-Ligand

This movie reviews the basic interaction between pre-osteoblasts and pre-osteoclasts that results in formation and activation of the osteoclast.

RANK-Ligand inhibitors have been undergone phase 2 testing and phase 3 studies are underway. The major questions are whether these medications will prevent fractures and whether they will have any side effects on the immune system.

Updated 5/10/06