Cryo-electron microscopy of biological macromolecules and complexes

Department of Biological Structure
University of Washington

Course DescriptionLearning objectivesCredits and hours

Spring Quarter 2017
Instructor: Liguo Wang

Tel: 206-6167894

Class meets in  HSB E212 [ Where is this classroom? ]
Tuesday & Thursday 10:00-11:20

Office Hours: Thursday, 11:30-12:00pm
Office Location: HSB G519

Course Description

Introduction to high-resolution cryo-electron microscopy (cryoEM); image formation and three-dimensional reconstruction theories and available software; hands-on experience using the cryoEM facility for data collection and analysis; presentations on student projects.

Learning objectives

Students will learn both the theory and application of cryo-electron microscopy as an emerging new technique that allows biological macromolecules and complexes to be studied at all levels of resolution ranging from their cellular organization to near atomic detail.

Credits and hours

An average of 3 hours per week over 10 weeks based on ten lectures of 1.5 hours each; three hands-on experience of 3 hours each; and two 1.5-hour sessions for project presentations.

Last updated: Saturday, 3/27/2017