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Critically Appraised Topics: Prognosis (December 07) In a 78-year-old man with severe COPD (FEV1 < 1), who meets criteria for home O2 but refuses to use it, and who is still smoking, what is his 5-year mortality? (October 07) In a 30 year old male tobacco user with cumulative 15 pack-year history of exposure what is his subsequent risk of dying from lung cancer if he stops smoking now? (April 07) In a 42 year old female with recurrent DVTE and negative thrombotic workup what is the lifetime likelihood of futher recurrence of PE/death? (March 07) For a 20 year old woman HSV-2 negative entering a relationship with a male with HSV-2 what is the annual risk of acquiring genital herpes? Is the risk mitigated by condoms? (January 07) In a 45 yo man w/ afib and CHF (35%), HTN, DM, wants to stop coumadin, what is his risk for CVA off anti-coagulation? (November 06) In a 59 yo man with history of heavy alcohol use and hospitalization due to cirrhosis, what is the risk of death with or without abstinence from alcohol? (September 06) In a 30 yo man w/ hx of IVDU, elevated ALT, heavy alcohol use, and newly diagnosed chronic hepatitis C, what is the risk of progression to cirrhosis and how does alcohol use affect that risk? (July 06) In a 45 year old with a finger laceration what is the risk of digital ischemia if using epinephrine with a local anesthetic? If the risk is minimal are there any benefits?
(May 06)
In a healthy 20 yo female with new diagnosis of breast fibroadenoma, what is her lifetime risk of breast cancer? (January 06) In a 62yo male with known CAD s/p CABG, what is the risk of recurrent MI if he has normal cholesterol levels? (December 05) In a patient with Barrett's esophagus on a proton pump inhibitor, what's the risk of developing esophageal cancer? (September 05)
In a 49 year-old woman with an FEV1 of 36% predicted and severe COPD, what is her risk of death in 1 year? (July 05)
In a 55 year old male with 3 actinic keratosis, what is the lifetime risk of devoloping squamous cell skin cancer?
Update this search in PubMed (June 05)
In an anti-coagulated patient, what is the likelihood of significant bleeding complications with the placement of central line? (May 05)
In patients with known NASH, diagnosed by biopsy, what is likelihood of the development of cirrhosis? (February 05)
In patients with known COPD, diagnosed by PFTs, what is the mortality rate for patients after a first hospitalization?
Update this search in PubMed* (January 05)
How many men with no comorbidities diagnosed with localized prostate cancer (with a certain pathologic finding) after the age of 65 die of their cancer?
(November
04)
Does poorly controlled hypertension increase time to progression to hemodialysis in patients without diabetes?
Update this search in PubMed*
An 84 year old woman with multiple co-morbidities is found to have an aneurysm measured at 5.2 cm. What is her risk of rupture within the coming year, particularly in light of her substantial operative risk?
Update this search in PubMed* (September 04)
In a patient with type II diabetes and persistent hyperglycemia (A1C of 10), what is the risk of cardiovascular complications?
Update this search in PubMed* (August 04)
For patients with essential thrombocytosis, what is the risk of vascular complications (eg stroke, MI) at a platelet count > 1,000,000?
*This embedded search was created by Sherry Dodson, Clinical Medical Librarian at the UW Health Sciences Libraries. The link will take you directly to current and relevant citations in PubMed which automatically update as new studies are published and indexed. If you would like to see the search terms used, click on the Details tab in PubMed. The search strategy can be seen at the bottom under User Query.
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