Fish 510 Quantitative Genetics
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This page will be used to disseminate readings and data sets. Check frequently!

April 1
Here is the reading for this week, in pdf format.
Barker JSF, Thomas RH (1987) A Quantitative Genetic Perspective on Adaptive Evolution. In: Genetic Constraints on Adaptive Evolution (ed. Loeschcke V), pp. 3-23. Springer-Verlag, Berlin.

If you need a refresher on quantitative traits, look at the lecture notes from Fish 444.

April 08
Here is Exercise 1, in Excel format, to be used in class (right click on file, select "Save Target As").

April 15
Here is Exercise 2 in Excel format.

April 22
Here is the solution to Exercise 1 and Exercise 2 (with corrected text).

Here are the three recommended readings in pdf format. (Scanned, and slow to print).

Jacquard A (1983) Heritability: One word, three concepts. Biometrics 39, 465-477.

Lewontin RC (1974) The analysis of variance and the analysis of causes. American Journal of Human Genetics 26, 400-411.
(Examines misuse of Quantitative Genetic estimates in human studies)

Klein TW, DeFries JC, Finkbeiner CT (1973) Heritability and genetic correlation: Standard errors of estimates and sample size. Behavior Genetics 3, 355-364.
(Useful for study design)

April 29
Reading for next week:
Roff DA (1997) Evolutionary Quantitative Genetics. Chapman & Hall, New York. 493pp.
Ch 3: The Genetic Correlation.

May 13
Exel Exercises for this week:
Exercise 3
Response to selection

G Matrix
Heterosigma

Here is a really cool review paper on the use of G matrices in comparitive quantitative genetics - nice explanations, and a good read!
Steppan SJ, Phillips PC, Houle D (2002) Comparative quantitative genetics: evolution of the G matrix. Trends in Ecology and Evolution 17, 320-327.

Reading for next week:
Shaw RG (1987) Maximum-Likelihood approaches applied to Quantitative Genetics of Natural Populations. Evolution 41, 812-826.

May 19

Link to the zipped file for DFREML and Quercus. Right click and save.

May 27

Here are the excel files for line cross analyses: Jstmeans and jstvars.

June 3

Here is the paper to accompany today's lecture;

Hard JJ, Bradshaw WE, Holzapfel CM (1992) Epistasis and the genetic divergenec of photoperiodism between populations of the pitcher-plant mosquito, Wyeomyia smithii. Genetics 131, 389-396.