HuBio 564: Principles of Pharmacology II
Case Study 3
A 45 year old man presents to your office with complaints of decreased sleep, irritability, difficulty concentrating, excited mood, and increased libido for one week. He is on probation at work after telling the head of his corporate office that she didn't know how to run the business and that he could double their profits in just six weeks. His wife has moved out, saying she can't deal with him any more, but he says that she's just jealous of his brilliance. Four years ago he had a significant depression, with increased sleep, low self esteem, trouble concentrating, anxiety, and hopelessness. He received no specific treatment at that time. He has felt this way in the past once or twice before, but it was milder. He takes a thiazide diuretic for hypertension, but denies other health problems or substance abuse issues.
1. What is the diagnosis?
2. What medication(s) will you recommend, how will you determine the therapeutic dose, and what side effects might you counsel regarding? Focus on one initial strategy.
3. Based on your medication choice, what lab tests should you obtain?
4. Are there any medications you would avoid as monotherapy?
5. What adjunctive treatments may be necessary?
6. For how long would you continue treatment?
Use the Submit Case Report button or go to http://depts.washington.edu/phcol/case_sub.html to submit this case.
Please check the status of your work through the My Grade link on the SOMOC page.
