Dermis: Cells

Key concept

The cells of the dermis are derived from somite mesoderm. Fibroblasts, which secrete the connective tissue matrix, Schwann cells, which will form the perineural structures, and endothelial cells, which form the blood vessels differentiate very early from the primordial dermal mesenchyme. Adipocytes, which form the fat lobules of the subcutaneous tissue arise later from the same source. Macrophages, pericytes, and mast cells appear last.

Bullet Summary

• Week 6: Cellular primordial dermis
• Week 8: Fibroblasts, Endothelial cells, Schwann cells
• Week 14: Adipocytes
• Week 20: Macrophages, Pericytes, Mast cells

To see how cells develop click on one of the buttons below:

Week 6
Week 8
Week 14
Week 20