Dermis: Organization and Matrix week 6

Cellular primordial dermis

Densely packed stellate syncytial mesenchymal cells are suspended in a watery matrix composed mostly of hyaluronic acid and a few collagen fibrils. Collagen is identified by the typical of banding pattern.

Cellular Primordial Dermis

This thin-section light micrograph shows a flattened "pavement epithelium" periderm, and a single layer of keratinocytes over a highly cellular presumptive dermis (the next six or eight cells down). One early vascular structure with a lumen is seen on the right side of the image. Note how little extracellular matrix is present and compare to later points in development. Also note how homogeneous the cell population appears.