Dermis: Organization and Matrix week 9

Transition to fibrous matrix begins

At week 9 of gestation the dermis begins a transition from cellular to fibrous. The mesenchymal cells become separated and they secrete more fibrous material extracellularly. At the same time, the water content of the dermis begins to decrease as the content of sulfated glycosaminoglycans decreases. As the dermis becomes more dense, changes are also occurring at other levels.