Tom Matula Ph.D.
Applied Physics Laboratory (Center for Industrial & Medical
"Cavitation in Diagnostic and Therapeutic Applications"
This talk will describe cavitation that occurs in diagnostic and
ultrasound. In diagnostic ultrasound, cavitation is most often related
injection of ultrasound contrast agents, small bubbles used to enhance
overall contrast in imaging. These agents are also being developed as
therapeutic agents for targeted drug delivery. At high negative acoustic
pressures associated with therapeutic ultrasound, cavitation occurs in
bloodstream and fluid-filled cavities. Examples of intense acoustic
include lithotripsy, High Intensity Focused Ultrasound (HIFU),
wave therapy for musculoskeletal conditions. Various examples, and
research directions will be discussed.