ME
537 Fluid Mechanics of the
Cardiovascular System
http://courses.washington.edu/mengr537
Class time: Mon, Wed 3:30-4:50 Zoom
Instructor:
|
Professor Alberto
Aliseda
office: MEB 306
tel: 543-4910
email: aaliseda@u.washington.edu
office hours: Zoom by appointment
|
Course Description
- The material in this course will provide the student
with the fundamental background in fluid mechanics and the
necessary understanding of the anatomy and physiology of the
human vascular system to carry out research in the area of
cardiovascular fluid mechanics. Topics that will be covered
include normal physiological flow in veins and arteries, flow
related pathologies such as thrombosis, atherosclerosis,
stenosis, aneurysms, heart valve dysfunction. Applications to
mechanics-based medical devices and therapies will also be a
significant part of the course.
Homework
Reading Assignments:
Heart Anatomy and Physiology: Chapter
1. Physical Principles Circulation
Circulation.
Chapter
2. The Heart
Mechanical
Properties Living Tissue. Chapter
3. Blood Rheology
Mechanical
Properties Living Tissue. Chapter
5. Blood Flow Heart Lungs Arteries Veins
Circulation.
Chapter 3. Sections 1-7. Flow in
Arteries
Circulation.
Chapter 3. Sections 8-12.
Wave Transmission in
Arteries
Syllabus
- Primer on Cardiovascular
Anatomy and
Physiology.
Weeks 1&2
- Introduction to Fluid and
Solid Mechanics of the Vascular
System:
Weeks 3&4
- Non-Linear
Stress-Strain constitutive
equations and Rheology.
Some classical problems in
Cardiosvacular Fluid Mechanics:
Poiseuille,
Weeks 5&6
Womersley, pulsatile flow in a
tube with slowly varying cross
section,
pulsatile flow in a curved vessel,
pulsatile flow in a collapsible tube.
Flow in complex geometries:
Flow separation,
recirculation
Weeks 7&8
and transition to turbulence
Specific problems in
Cardiovascular
Mechanics:
Weeks 9&10
Flow in Heart Valves, Stenotic
Arteries and Partially Occluded Veins.
Textbook
- There is no single course textbook,
but the material for the course has
been developed mostly from the
following books:
- 1. Fung, Y. C. Biodynamics,
Circulation . Springer-Verlag, New
York, 1984.
2. Fung, Y. C., Biomechanics: Motion,
Flow, Stress, & Growth .
Springer-Verlag, New York, 1990.
3. Fung, Y. C., Biomechanics:
Mechanical Properties of Living Tissue
, 2 nd edition. Springer-Verlag, New
York, 1993.
4. Caro, C. G., Pedley, T. J.,
Schroter, R. C., Seed, W. A. The
Mechanics of the Circulation. Oxford
Medical Publications, Oxford, 1978.
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Grading
- Homework
30%
- Personal Project
50%
- Class
Discussion
20%
University of Washington Emergency
Procedures
-
- Emergency procedures for building
evacuation, earthquake, fire,
hazardous materials,
- and other potential
problems are at the following website:
-
- http://www.washington.edu/admin/business/oem/mitigate/emerg_proc_poster.pdf