LECTURE SCHEDULE AND READING ASSIGNMENTS

All course readings will be posted as they become available. Please click on links below for lecture notes and journal papers. If you have trouble accessing a link or downloading an article, email Carmen (carmen.zelaya@sbri.org).

1. 9/27/07 Overview of course, Causes of morbidity and mortality (Parsons).

• Link to reading assignment.
• PH in the News

(from Marilyn) Hi all, please review this short slide show--it has a couple clarifications from today and also a few of the slides I did not get to cover that I would like you to particularly think about. Mortality Points

2. 10/02/07 Introduction to the Microbial World / Innate and Acquired Immunity to Pathogens (Lukehart)

Required:

• Nature. 2000 Aug 17;406(6797):782-7
• Curr Opin Immunol. 2004 Aug;16(4):483-7
• PH in the News

General Reading: (all on reserve at HS library)

• Medical Microbiology by Murray et al.
• Sherris Medical Microbiology (Chapter 8 is on Immune Response to Infection)
• Janeway's Immunobiology

3. 10/04/07 Pathogenesis I: Attachment and Invasion: (Lukehart)

Required reading for 10/04/07 and 10/09/07:

• Microbiol Molec Biol Rev 1997; 61: 136-69

Sign up for panel discussions

4. 10/09/07 Pathogenesis II: Persistence and Immune Evasion (Lukehart) also, Pathogenesis III : Toxins and Tissue Damage

• Required: Same review as above (Microbiol Molec Biol Rev 1997; 61: 136-69)
• PH in the News

5. 10/11/07 Controlling Infections with Vaccines: Science, Practice, and Clinical Trials (Stamatatos)

• Making markets for vaccines
• J Virol 2005 Vol 79 p.1062
• General Reading: Vaccines by Plotkin et al.
• PH in the News

6. 10/16/07 Tuberculosis and Disease Surveillance (Cangelosi)

• Lancet Infect Dis. 2007 May;7(5):328-37
• Nat Rev Microbiol. 2005 Aug;3(8):656-62
• PH in the News

7. 10/18/07 Identifying New Infectious Agents (Totten)

• Clin Microbiol Rev. 1996; 9: p18-33
• PNAS 2002; 99: 15687-692
• JID 2001; 183: 1229-37

8. 10/23/07 PANEL DISCUSSION I

9. 10/25/07 AIDS: A Global View (Farquhar)

• The Lancet 368 Aug 5, 2006
• Nat Med 2003; 9(7): 839-43
• PH in the News

Here is a link to another reading which is long, but very informative. Printing not recommended due to length.

Midterm distributed

10. 10/30/07 Biological Warfare / Discussion (Parsons)

Required:

• Toxicol Appl Pharmacol. 2004;199(1):71-84
• J Virol. 2001 Feb;75(3):1205-10

Recommended:

• Biosecur Bioterror. 2006; 4(2):113-27

In addition, here are questions to consider after reading the mousepox paper. Please visit http://www.fas.org/biosecurity/education/dualuse/FAS_Jackson/4_B.html to get started thinking about the ethical issues.

• PH in the News

11. 11/01/07 Controlling Infections with Drugs: Antibiotics and Antibiotic Resistance (Roberts)

• Lancet Infect Dis 2005; 5: 481–93 (Part 1)
• Lancet Infect Dis 2005; 5: 568–80 (Part 2)

Turn in midterm exam.

12. 11/06/07 Emergence and Reemergence of Diseases / Discussion (Kimball)

• Annu Rev Public Health 2005 26:191-212
• Eco Health 2004 1:39-49
• PH in the News

13. 11/08/07 PANEL DISCUSSION II

* Do not forget that your final paper outlines are due 11/16 (by email or in class). Remember that the topic should be a controversial public health issue.

14. 11/13/07 H5N1 Influenza on the Horizon / Discussion (Parsons and Stamatatos).

Required:

• Science 2006; Vol 312: p.854
• Influenza mortality

Recommended:

• Clin Micro Rev 2007, 243-267

15. 11/15/07 Biology of Obesity (Morton)

• Nature 2006 443: 289-295
• PH in the News

16. 11/20/07 Chronic Disease: Diabetes--Health and Lifestyle (Zelaya)

• Science 2006 313:175-176
• New York Times Jan 10, 2006

• PH in the News (Rob)
• PH in the News (Katherine)

17. 11/27/07 PANEL DISCUSSION III
*CLASS WILL START AT 8:00 AM*

18. 11/29/07 Politics of Food and Health: Food and Water Safety / Discussion (Parsons).

• Proc Nut Soc 2000 59:619-629
• PH in the News

Small group discussions: how do we interpret our governments advice? What are the ramifications?

• Research your group topic (eating more fruits/vegetables, moderating sugar intake, or maintaining healthy weight)
  * Optional draft due

19. 12/04/07 Ethics in Public Health: the Tuskegee example (Lukehart)

• Tuskegee Study Timeline
• Arch Intern Med 160: 585-598
• PH in the News

Books for those interested in reading more:

• "Bad Blood" by James Jones
• "The Tuskegee Syphilis Study" by Fred Gray

20. 12/06/07 Malaria Research in the Developing World: the Science and the Reality (Duffy, Fried)

• Nature 1998 395: 851-852
• The Lancet 2007 369: 874-877
• PH in the News

READINGS/VIDEOS ON RESERVE AT HEALTH SCIENCES LIBRARY

• Plotkin, Orenstein. Vaccines, 4th ed.
• Deadly Deception
• 20/20 interview on Tuskegee
• "Miss Evers' Boys" - a play
• Murray, Medical Microbiology.
• general microbiology textbook
• Sherris Medical Microbiology

RECOMMENDED ADDITIONAL READING LIST ON TOPICS OF INTEREST

click here for the list