Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, October 6, 1999
Room T-530/530A HSC

Speaker: Stan McKnight
Topic: Metered on-RAMPs for receptors headed to the membrane

References:

  1. McLatchie LM, Fraser NJ, Main MJ, Wise A, Brown J, Thompson N, Solari R, Lee MG, and Foord SM. (1998) "RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor." Nature 393(6683):333-339.

  2. Fraser NJ, Wise A, Brown J, McLatchie LM, Main MJ, and Foord SM. (1999) "The amino terminus of receptor activity modifying proteins is a critical determinant of glycosylation state and ligand binding of calcitonin receptor-like receptor." Mol Pharmacol 55(6):1054-1059.

  3. Christopoulos G, Perry KJ, Morfis M, Tilakaratne N, Gao Y, Fraser NJ, Main MJ, Foord SM, and Sexton PM. (1999) "Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product." Mol Pharmacol 56(1):235-242.

  4. Fluhamann B, Muff R, Hunziker W, Fischer JA, and Born W. (1995) "A human orphan calcitonin receptor-like structure." Biochem Biophys Res Commun 206(1):341-347.

  5. Drake WM, Ajayi A, Lowe SR, Mirtella A, Bartlett TJ, and Clark AJ. (1999) "Desensitization of CGRP and adrenomedullin receptors in SK-N-MC cells: implications for the RAMP hypothesis." Endocrinology 140(1):533-537.

Reviews:
  1. Foord SM and Marshall FH. (1999) "RAMPs: accessory proteins for seven transmembrane domain receptors." Trends Pharmacol Sci 20(5):184-187.

  2. Wimalawansa SJ. (1997) "Amylin, calcitonin gene-related peptide, calcitonin, and adrenomedullin: a peptide superfamily. Crit Rev Neurobiol 11(2-3):167-239.


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