Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, November 3, 1999
Room T-530/530A HSC

Speaker: Jeremy Celver
Topic: Transcription factor MEF2: Role in Apoptosis

References:

  1. Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A. (1999) Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain. Cell 97:703-716.

  2. Mao Z, Bonni A, Xia F, Nadal-Vicens M, Greenberg ME 1(999) Neuronal Activity-Dependent Cell Survival Mediated by Transcription Factor MEF2. Science Oct 22;286(5440):785-790

  3. Youn HD, Sun L, Prywes R, Liu JO (1999) Apoptosis of T Cells Mediated by Ca(2+)-Induced Release of the Transcription Factor MEF2. Science Oct 22;286(5440):790-793

  4. Zhao M, New L, Kravchenko VV, Kato Y, Gram H, di Padova F, Olson EN, Ulevitch RJ, Han J (1999) Regulation of the MEF2 family of transcription factors by p38. Mol Cell Biol Jan;19(1):21-30

  5. Mao Z, Wiedmann MJ (1999) Calcineurin enhances MEF2 DNA binding activity in calcium-dependent survival of cerebellar granule neurons. Biol Chem Oct 22;274(43):31102-7

  6. Ornatsky OI, McDermott JC (1996) MEF2 protein expression, DNA binding specificity and complex composition, and transcriptional activity in muscle and non-muscle cells. J Biol Chem Oct 4;271(40):24927-33

  7. Naya FJ, Wu C, Richardson JA, Overbeek P, Olson EN (1999) Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene. Development May;126(10):2045-52

  8. Zetser A, Gredinger E, Bengal E (1999) mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor. J Biol Chem Feb 19;274(8):5193-200 p38

  9. Black BL, Ligon KL, Zhang Y, Olson EN (1996) Cooperative transcriptional activation by the neurogenic basic helix-loop-helix protein MASH1 and members of the myocyte enhancer factor-2 (MEF2) family. J Biol Chem Oct 25;271(43):26659-63

  10. Gunthorpe D, Beatty KE, Taylor MV (1999) Different Levels, but Not Different Isoforms, of the Drosophila Transcription Factor DMEF2 Affect Distinct Aspects of Muscle Differentiation. Dev Biol Nov 1;215(1):130-145

  11. Bi W, Drake CJ, Schwarz JJ (1999) The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF. Dev Biol Jul 15;211(2):255-67

  12. Chin ER, Olson EN, Richardson JA, Yang Q, Humphries C, Shelton JM, Wu H, Zhu W, Bassel-Duby R, Williams RS (1998) A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. Genes Dev Aug 15;12(16):2499-509

  13. Ornatsky OI, Andreucci JJ, McDermott JC (1997) A dominant-negative form of transcription factor MEF2 inhibits myogenesis. J Biol Chem Dec 26;272(52):33271-8

Reviews:

  1. Shore P, Sharrocks AD (1995) The MADS-box family of transcription factors. Eur J Biochem Apr 1;229(1):1-13

  2. Molkentin JD, Olson EN (1996) Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors. Proc Natl Acad Sci U S A Sep 3;93(18):9366-73

  3. Brand NJ (1997) Myocyte enhancer factor 2 (MEF2). Int J Biochem Cell Biol Dec;29(12):1467-70

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