Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, January 5, 2000
Room T-530/530A HSC

Speaker: Bill Catterall
Topic: ROCs and SOCs: Interaction of IP3 Receptors and trp Calcium Channels in Capacitative Calcium Entry

Review:

  1. Putney, Jr., J.W. (1999) TRP, inositol 1,4,5-triphosphate receptors, and capacitative calcium entry. Proc. Natl. Acad. Sci. U.S.A. 96:14669-14671.

References:

trp Channels and Capacitative Calcium Entry

  1. Vaca, L., Sinkins, W.G., Hu, Y., Kunze, D., and Schilling, W.P. (1994) Activation of recombinant trp by thapsigargin in Sf9 insect cells. Am. J. Physiol. 267:C1501-C1505.

  2. Zhu, X., Jiang, M., Peyton, M., Boulay, G., Hurst, R., Stefani, E., and Birnbaumer, L. (1996) trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry. Cell 85:661-671.

Gating of trp by Interaction with IP3 Receptors

  1. Kiselyov, K., Xu, X., Mozhayeva, G., Kuo, T., Pessah, I., Mignery, G., Zhu, X., Birnbaumer, L., and Muallem, S. (1998) Functional interaction between InsP3 receptors and store-operated Htrp3 channels. Nature 396:478-482.

  2. Kiselyov, K., Mignery, G.A., Zhu, M.X., and Muallem, S. (1999) The N-terminal domain of the IP3 receptor gates store-operated hTrp3 channels. Mol. Cell 4:423-429.

  3. Zubov, A.I., Kaznacheeva, E.V., Nikolaev, A.V., Alexeenko, V.A., Kiselyov, K., Muallem, S., and Mozhayeva, G.N. (1999) Regulation of the miniature plasma membrane Ca2+ channel Imin by inositol 1,4,5-triphosphate receptors. J. Biol. Chem. 274:25983-25985.

  4. Boulay, G., Brown, D.M., Qin, N., Jiang, M., Dietrich, A., Zhu, M.X., Chen, Z., Birnbaumer, M., Mikoshiba, K., and Birnbaumer, L. (1999) Modulation of Ca2+ entry by polypeptides of the inositol 1,4,5-triphosphate receptor (IR3R) that bind transient receptor potential (TRP): Evidence for roles of TRP and IP3R in store depletion-activated Ca2+ entry. Proc. Natl. Acad. Sci. U.S.A. 96:14955-14960.

SNARE Proteins and Cortical Cytoskeleton in Capacitative Calcium Entry

  1. Yao, Y., Ferrer-Montiel, A.V., Montal, M., and Tsien, R.Y. (1999) Activation of store-opoerated Ca2+ current in Xenopus oocytes requires SNAP-25 but not a diffusible messenger. Cell 98:475-485.

  2. Patterson, R.L., van Rossum, D.B., and Gill, D.L. (1999) Store-operated Ca2+ entry: Evidence for a secretion-like coupling model. Cell 98:487-499.


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