Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, November 1, 2000
Room T-473 HSC

Speaker: Doug Howe
Topic: Stem Cells and CNS cell transplant therapy

Reviews:

  1. Bjšrklund A and Lindvall O. (2000) Cell replacement therapies for central nervous system disorders. Nature Neuroscience 3(6): 537-544.

  2. Lindvall O (1999) Cerebral implantation in movement disorders: State of the art. Move. Dis. 14(2): 201-205.

  3. Van der KooY D and Weiss S (2000) Why stem cells? Science 287: 1439-1441.

  4. Gage FH (2000) Mammalian neural stem cells. Science 287: 1433-1438.

  5. Shihabuddin LS et al. (1999) The search for neural progenitor cells: prospects for the therapy of neurodegenerative disease. Mol. Med. Tod. 5: 474-480.

  6. Momma et al. (2000) Get to know your stem cells. Curr. Opin. Neurobiol. 10: 45-49.

  7. Gage FH et al. (1998) Multipotent progenitor cells in the adult dentate gyrus. J. Neurobiol. 36: 249-266.

Reports:

  1. Kordower JH et al. (1995) Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with ParkinsonÕs disease. NEJM 332(17): 1118-1124.

  2. Philpott LM et al. (1997) Neuropsychological functioning following fetal striatal transplantation in HuntingtonÕs chorea: Three case presentations. Cell Trans. 6(3): 203-212.

  3. Winkler C et al. (1999) Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat Parkinson model and promote the effects obtained by intrastriatal dominergic transplants. Exper. Neurol. 155: 165-186.

  4. Kordower JH et al. (1998) Fetal nigral grafts survive and mediate clinical benefit in a patient with ParkinsonÕs disease. Move. Dis. 13(3): 383-393.

  5. Brasted PJ et al. (1999) Associative plasticity in striatal transplants. Proc. Natl. Acad. Sci. 96: 10524-10529.

  6. Lee S-H et al. (2000) Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nature Biotech. 18: 675-679.

  7. Magavi SS et al. (2000) Induction of neurogenesis in the neocortex of adult mice. Nature 405: 951-955.


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