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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, November 1, 2000
Room T-473 HSC
Speaker: Doug Howe
Topic: Stem Cells and CNS cell transplant therapy
Reviews:
Bjrklund A and Lindvall O. (2000) Cell replacement therapies for central nervous system disorders. Nature Neuroscience 3(6): 537-544.
Lindvall O (1999) Cerebral implantation in movement disorders: State of the art. Move. Dis. 14(2): 201-205.
Van der KooY D and Weiss S (2000) Why stem cells? Science 287: 1439-1441.
Gage FH (2000) Mammalian neural stem cells. Science 287: 1433-1438.
Shihabuddin LS et al. (1999) The search for neural progenitor cells: prospects for the therapy of neurodegenerative disease. Mol. Med. Tod. 5: 474-480.
Momma et al. (2000) Get to know your stem cells. Curr. Opin. Neurobiol. 10: 45-49.
Gage FH et al. (1998) Multipotent progenitor cells in the adult dentate gyrus. J. Neurobiol. 36: 249-266.
Reports:
Kordower JH et al. (1995) Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with ParkinsonÕs disease. NEJM 332(17): 1118-1124.
Philpott LM et al. (1997) Neuropsychological functioning following fetal striatal transplantation in HuntingtonÕs chorea: Three case presentations. Cell Trans. 6(3): 203-212.
Winkler C et al. (1999) Intranigral transplants of GABA-rich striatal tissue induce behavioral recovery in the rat Parkinson model and promote the effects obtained by intrastriatal dominergic transplants. Exper. Neurol. 155: 165-186.
Kordower JH et al. (1998) Fetal nigral grafts survive and mediate clinical benefit in a patient with ParkinsonÕs disease. Move. Dis. 13(3): 383-393.
Brasted PJ et al. (1999) Associative plasticity in striatal transplants. Proc. Natl. Acad. Sci. 96: 10524-10529.
Lee S-H et al. (2000) Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nature Biotech. 18: 675-679.
Magavi SS et al. (2000) Induction of neurogenesis in the neocortex of adult mice. Nature 405: 951-955.
2000-2001 Journal Club Schedule
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