Pharmacology 514:
Current Topics in Pharmacology
Journal Club




Instructions for

JClub Archive

Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, January 24, 2001
Room T-473 HSC

Speaker: Heidi Iverson
Topic: A Tasty Talk: The umami and bitter taste receptors


  1. Adler E, Hoon MA, Mueler KL, Chandrashekar J, Ryba NJP, Zuker CS. A novel family of mammalian taste receptors. Cell 2000 Mar 17;100(6):693-702.

  2. Chandrashekar J, Mueller KL, Hoon MA, Adler E, Feng L, Guo W, Zuker CS, Ryba NJP. T2Rs function as bitter taste receptors. Cell 2000 Mar 17;100(6):703-11.

  3. Chaudhari N, Landin AM, Roper SD. A metabotropic glutamate receptor variant functions as a taste receptor. Nat Neurosci 2000 Feb;3(2):113-9.

  4. Chaduhari N, Yang H, Lamp C, Delay E, Cartford C, Than T, Roper S. The taste of monosodium glutamate: Membrane receptors in taste buds. J Neurosci 1996 16(12):3817-3826.

  5. Hoon MA, Adler E, Lindemeier J, Battey JF, Ryba NJP, Zuker CS. Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity. Cell 1999 Feb 19;96(4):541-51.

  6. Huang L, et. al. Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. Nature Neuroscience 1999 2:1055-1062.

  7. Matsunami H, Montmayeur JP, Buck LB. A family of candidate taste receptors in human and mouse. Nature 2000 Apr 6;404(6778):601-4.

  8. McLaughlin SK, McKinnon PJ, Margolskee RF. Gustducin is a taste-cell specific G protein closely related to the transducins. Nature 1992 357:563-569.

  9. Wong GT, Gannon KS, Margolskee RF. Transduction of bitter and sweet taste by gustducin. Nature 1996 Jun 27;381(6585):796-800.

  1. Gilbertson, T. A., Damak, S., Margolskee R.F. The molecular physiology of taste transduction. Curr Opin Neurobiol 2000 Aug;10(4):519-27.

  2. Kinnamon SC, Margolskee RF. Mechanisms of taste transduction. Curr Opinion Neurobiol 1996 6:506-513.

  3. Spileman AI. Gustducin and its role in taste. J Dent Res 1998 77:539-544.

2000-2001 Journal Club Schedule

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