Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, May 2, 2001
Room T-473 HSC

Speaker: Neil Nathanson
Topic: The Ins and Outs of Glutamate Receptors: Making Silent Synapses Shout and Shouting Synapses Shut Up

References:

  1. Isaac JT, Nicoll RA, Malenka RC. (1995) Evidence for silent synapses: implications for the expression of LTP. Neuron 15(2):427-34.

  2. Shi SH, Hayashi Y, Petralia RS, Zaman SH, Wenthold RJ, Svoboda K, Malinow R. (1999) Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation. Science 284(5421):1811-6.

  3. Hayashi Y, Shi SH, Esteban JA, Piccini A, Poncer JC, Malinow R. (2000) Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science 287(5461):2262-7.

  4. Wang and Linden. (2000) Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis. Neuron 25:635.

  5. Xia J, Chung HJ, Wihler C, Huganir RL, Linden DJ. (2000) Cerebellar long-term depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins. Neuron 28(2):499-510.

Reviews:
  1. Lin JW, Sheng M. (1998) NSF and AMPA receptors get physical. Neuron 21(2):267-70.

  2. Scannevin and Huganir. (2000) Postsynaptic organization and regulation of excitatory synapses. Nature Reviews Neurosci 1:133

  3. Turrigiano. (2000) AMPA receptors unbound: membrane cycling and synaptic plasticity. Neuron 26:5


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