Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, October 17, 2001
Room T-473 HSC
(NOTE: ROOM NUMBER HAS CHANGED FROM T-530/530A TO T-473)

Speaker: James Surapisitchat
Topic: Survinin Apoptosis- A Inhibitor of Apoptosis Protein (IAP)

References:

  1. Ambrosini G., C. Adida, et al. (1997). "A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma." Nat Med. 3(8): 917-21.

  2. Grossman, D., P. J. Kim, et al. (2001). "Transgenic expression of survivin in keratinocytes counteracts UVB- induced apoptosis and cooperates with loss of p53." J Clin Invest 108(7): 991-999.

  3. Mesri, M., M. Morales-Ruiz, et al. (2001). "Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting." Am J Pathol. 158(5): 1757-65.

  4. Mesri, M., N. R. Wall, et al. (2001). "Cancer gene therapy using a survivin mutant adenovirus." J Clin Invest. 108(7): 981-90.

  5. O'Connor, D. S., D. Grossman, et al. (2000). "Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin." Proc Natl Acad Sci USA. 97(24): 13103-7.

  6. O'Connor, D. S., J. S. Schechner, et al. (2000). "Control of apoptosis during angiogenesis by survivin expression in endothelial cells." Am J Pathol. 156(2): 393-8.

  7. Olie, R. A., A. P. Simoes-Wust, et al. (2000). "A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy." Cancer Res. 60(11): 2805-9.

Reviews:
  1. Hengartner, M. O. (2000). "The biochemistry of apoptosis." Nature. 407(6805): 770-6.

  2. Reed, J. C. (2001). "The Survivin saga goes in vivo." J Clin Invest 108(7): 965-9. J Clin Invest. 108(7): 965-9.


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