Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, October 31, 2001
Room T-473 HSC
(NOTE: ROOM NUMBER HAS CHANGED FROM T-530/530A TO T-473)

Speaker: Anke Witting
Topic: Control of Trk Signaling by Membrane Trafficking

References:

  1. Saragovi HU, Zheng W, Maliartchouk S, DiGuliemo GM, Mawal YR, Kamen A, Woo SA, Cuello AC, Debeir T and Neet KE. (1998) "A TrkA-selective, fast internalizing nerv growth factor-antibody complex induces trophic but not neuritogenic signals." J. Biol. Chem. 273(52): 34933-40.

  2. Zhang Y, Moheban DB, Conway BR, Bhattacharyya A and Segal RS. (2000) "Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation." J. Neurosci. 20:5671-78.

  3. Kuruvilla R, Ye H and Ginty DD. (2000) "Spatially and functionally distinct roles of the PI3-K effector pathway during NGF signaling in sympathetic neurons". Neuron 27:499-512

  4. York RD, Molliver DC, Grewal SS, Stenberg PE, McCleskey EW and Stork PJS. (2000) "Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1". Mol. Cell. Biol. 20:18069-83

Reviews:
  1. Huang EJ and Reichardt LF. (2001) "Neurotrophins:roles in neuronal development and function". Annu. Rev. Neurosci. 24:677-736

  2. Patapoutian A and Reichardt LF. (2001) "Trk receptors:mediators of neurotrophin action". Current Opinion in Neurobiology. 11:272-280

  3. McPherson PS, Kay BK and Hussain NK. (2001) "Signaling on the endocytic pathway". Traffic 2:375-384


2001-2002 Journal Club Schedule
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