Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, November 7, 2001
Room T-473 HSC
(NOTE: ROOM NUMBER HAS CHANGED FROM T-530/530A TO T-473)

Speaker: Charles Chavkin
Topic: Feeling shaky? Forget Cipro, start taking SAHA

References:

  1. Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, Gohler H, Wanker EE, Bates GP, Housman DE, Thompson LM. (2000) "The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription." Proc. Natl. Acad. Sci. USA, 97:6763-6768.

  2. Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, Apostol BL, Kazantsev A, Schmidt E, Zhu YZ, Greenwald M, Kurokawa R, Housman DE, Jackson GR, Marsh JL, Thompson LM. (2001) "SHistone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila." Nature 413:739-43

Reviews:
  1. Zoghbi HY and Orr HT (2000) "Glutamine Repeats and Neurodegeneration". Annu. Rev. Neurosci. 23:217-247

  2. Bates GP (2001) "Exploiting expression". Nature 413:691-693 (news and views).

  3. Marks PA, Richon VM, Breslow R, Rifkind RA. (2001) "Histone deacetylase inhibitors as new cancer drugs." Curr Opin Oncol. (2001) Nov;13(6):477-483.


2001-2002 Journal Club Schedule
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