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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, January 9, 2002
Room T-473 HSC
(NOTE: ROOM NUMBER HAS CHANGED FROM T-530/530A TO T-473)
Speaker: Paul Amieux
Topic: Snail: A sluggish name for a very dynamic family of proteins
References:
Carver E., Jiang R., Lan Y., Oram K., Gridley T.: ") The Mouse Snail Gene Encodes a Key Regulator of the Epithelial-Mesenchymal Transition" Mol. Cell. Biol.. 2001 21(23):8184-8188.
Battle E., Sancho E., Franci C., Dominiguez D., Monfar M., Baulida J., de Herrerros A.:
"The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumor cells." Nature Cell Biology 2000 (2):84-89.
Cano A., Perez-Moreno M., Rodrigo I., Locascio A., Blanco M., del Barrio M., Portillo F., Nieto A.: "The transcription factor Snail controls epithelial to mesenchymal transitions by repressing E-cadherin expression.". Nature Cell Biology 2000 (2):76-83.
Burdsal C., Damsky C., Pedersen R.: "The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian streak" Development 1993 (118):829-844.
Reviews:
Hemavathy K., Asraf S., Ip Y.: "Snail/Slug family of repressors: slowly going into the fast lane of development and cancer". Gene 2000 (257):1-12.
2001-2002 Journal Club Schedule
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