Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, January 30, 2002
Room T-473 HSC
(NOTE: ROOM NUMBER HAS CHANGED FROM T-530/530A TO T-473)

Speaker: Cindy Reiner
Topic: Can too much Sno and Skiing be bad?; Ski/Sno regulation of TGF-beta signaling

References:

  1. Sun Y, Liu X, Eaton EN, Lane WS, Lodish HF, Weinberg RA.: "Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling." Molecular Cel. 1999 4:499.

  2. Xu W, Angelis K, Danielpour D, Haddad MM, Bischof O, Campisi J, Stavnezer E, Medrano EE.: "Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor." PNAS 2000. 97(11):5924.

  3. Shinagawa T, Nomura T, Colmenares C, Ohira M, Nakagawara A, Ishii S.: "Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice." Oncogene 2001. 20:8100.

  4. Leong GM, Subramaniam N, Figueroa J, Flanagan JL, Hayman MJ, Eisman JA, Kouzmenko AP.: "Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription." J. Biol. Chem. 2001. 276(21):18243.

  5. Stroschein SL, Wang W, Zhou S, Zhou Q, Luo K.: "Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein." Science 1999. 286:771 96-104.

  6. Sun Y, Liu X, Ng-Eaton E, Lodish HF, Weinberg RA.: "SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling." PNAS 1999. 96(22).

Reviews:
  1. Liu X, Sun Y, Weinberg RA, Lodish HF.: "Ski/Sno and TGF-beta signaling.". Cytokine and Growth Factor Reviews 2001 12(1):1.


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