Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, April 10, 2002
Room T-473 HSC
(NOTE: ROOM NUMBER HAS CHANGED FROM T-530/530A TO T-473)

Speaker: Katie MacLean
Topic: Out on a LIM: Combinatorial Regulation of Gene Transcription

References:

  1. Kenny D., Jurata L., Saga Y., Gill G; "Identification and Characterization of LMO4, an LMO Gene With a Novel Pattern of Expression During Embryogenesis" PNAS. 1998 Sep; (95): 11257-62.

  2. Jurata L., Pfaff S., Gill G; "The Nuclear LIM Domain Interactor NLI Mediates Homo- and Heterodimerization of LIM Domain Transcription Factors" J. Biol Chem 1998; 273(6): 3152-57.

  3. Visvader J., Venter D., Hahm K., Santamaria M., Sum E., O'Reilly L., White D., Williams R., Armes J., Lindeman G; "The LIM domain Gene LMO4 Inhibits Differentiation of Mammary Epithelial Cells In Vitro and is Overexpressed in Breast Cancer" PNAS 2001; 98(25): 14452-57.

  4. Sum E., Peng B., Yu x., Chen J., Byrne J., Lindeman G., Visvader J; "The LIM Domain Protein LMO4 Interacts with the Cofactor CtIP and the Tumor Supressor BRCA1 and Inhibits BRCA1 Activity" J. Biol. Chem. 2002 277(10): 7849-56,

Reviews:
  1. Bach, I.; "The LIM Domain: regulation by Association" Mechanisms of Development 2000; 91: 5-17.

  2. Dawid I., Breen J., Toyama R., "LIM Domains: Multiple Roles as Adapters and Functional Modifiers in Protein Interactions" TIG 1998; 14(4): 156-62.


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