Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, April 24, 2002
Room T-473 HSC
(NOTE: ROOM NUMBER HAS CHANGED FROM T-530/530A TO T-473)

Speaker: Danielle Ippolito
Topic: Stalking leukemia: Role of natural killer cells in hematopoietic stem cell transplantation

References:

  1. McSweeney PA, Niederwieser D, Shizuru JA, Sandmaier BM, Molina AJ, Maloney DG, Chauncey TR, Gooley TA, Hegenbart U, Nash RA, Radich J, Wagner JL, Minor S, Appelbaum FR, Bensinger WI, Bryant E, Flowers ME, Georges GE, Grumet FC, Kiem HP, Torok-Storb B, Yu C, Blume KG, Storb RF.; "Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects." Blood. 2001; 97(11):3390-400

  2. Wang JW, Howson JM, Ghansah T, Desponts C, Ninos JM, May SL, Nguyen KH, Toyama-Sorimachi N, Kerr WG.; " Influence of SHIP on the NK repertoire and allogeneic bone marrow transplantation." Science 2002; 295(5562):2094-7.

  3. Ruggeri L, Capanni M, Urbani E, Perruccio K, Shlomchik WD, Tosti A, Posati S, Rogaia D, Frassoni F, Aversa F, Martelli MF, Velardi A.; "Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants." Science 2002; 295(5562):2097-100.

  4. Tu Z, Ninos JM, Ma Z, Wang JW, Lemos MP, Desponts C, Ghansah T, Howson JM, Kerr WG; "Embryonic and hematopoietic stem cells express a novel SH2-containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein" Blood 2001 98(7):2028-38

  5. Marti F, Xu CW, Selvakumar A, Brent R, Dupont B, King PD; "LCK-phosphorylated human killer cell-inhibitory receptors recruit and activate phosphatidylinositol 3-kinase." PNAS 1998 95(20):11810-5

  6. Lowin-Kropf B, Held W.; "Positive impact of inhibitory Ly49 receptor-MHC class I interaction on NK cell development." J. Immunol. 2000 165(1):91-5

  7. Ruggeri L, Capanni M, Casucci M, Volpi I, Tosti A, Perruccio K, Urbani E, Negrin RS, Martelli MF, Velardi A; "Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation." Blood 1999 94(1):333-9.

  8. Shlomchik WD, Couzens MS, Tang CB, McNiff J, Robert ME, Liu J, Shlomchik MJ, Emerson SG; "Prevention of graft versus host disease by inactivation of host antigen-presenting cells." Science 1999 285(5426):412-5.

  9. Rosenzweig M, Connole M, Glickman R, Yue SP, Noren B, DeMaria M, Johnson RP; "Induction of cytotoxic T lymphocyte and antibody responses to enhanced green fluorescent protein following transplantation of transduced CD34(+)." Blood 2001 97(7):1951-9.

  10. Miura Y, Thoburn CJ, Bright EC, Sommer M, Lefell S, Ueda M, Nakao S, Hess AD; "Characterization of the T-cell repertoire in autologous graft-versus-host disease (GVHD): evidence for the involvement of antigen-driven T-cell response in the development of autologous GVHD." Blood 2001 98(3):868-76

Reviews:
  1. Maris M, Sandmaier BM, Maloney DG, McSweeney PA, Woolfrey A, Chauncey T, Shizuru J, Niederwieser D, Blume KG, Forman S, Storb R.; "Non-myeloablative hematopoietic stem cell transplantation." Transfus Clin Biol. 2001; 8(3):231-40.

  2. Feinstein L, Sandmaier B, Maloney D, McSweeney PA, Maris M, Flowers C, Radich J, Little MT, Nash RA, Chauncey T, Woolfrey A, Georges G, Kiem HP, Zaucha JM, Blume KG, Shizuru J, Niederwieser D, Storb R.; "Nonmyeloablative hematopoietic cell transplantation. Replacing high-dose cytotoxic therapy by the graft-versus-tumor effect." Ann N Y Acad Sci 2001; 938:328-37.

  3. Karre K; "A perfect mismatch." Science 2002; 295(5562):2029-31.


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