Current Topics in Pharmacology
12:30 PM, Wednesday, October 23, 2002
Room T-473 HSC
Speaker: Laura Beth Johnson
Topic: Anxiety and Agression in Neural Cell Adhesion Molecule Deficient Mice
Cremer H, Lange R, Christoph A, Plomann M, Vopper G, Roes J, Brown R, Baldwin S, Kraemer P, Scheff S, et al. Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits inspatial learning. Nature. February 3, 1994; 367(6462): 455-9.
Delling M, Wischmeyer E, Dityatev A, Sytnyk V, Veh RW, Karschin A, and Schachner M. The neural cell adhesion molecule regulates cell-surface delivery of G-protein-activated inwardly rectifying potassium channels via lipid rafts. Journal of Neuroscience. August 15, 2002; 22(16): 7154-64.
Stork O, Welzl H, Wotjak CT, Hoyer D,Delling M, Cremer H, and Schachner M. Anxiety and increased 5-HT1A receptor response in NCAM null mutant mice. Journal of Neurobiology. September 5, 1999; 40(3): 343-55.
Stork O, Welzl H, Cremer H, and Schachner M. Increased intermale aggression and neuroendocrine response in mice deficient for the neural cell adhesion molecule (NCAM). European Journal of Neuroscience. June 1997; 9(6): 1117-25.
Brown DA, London E. Functions of lipid rafts in biological membranes. Annual Review of Cell and Developmental Biology. 1998; 14: 111-36.
Crossin KL and Krushel LA. Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily. Developmental Dynamics. June 2000; 218(2): 260-79.
Hoyer D, Hannon JP, and Martin GR. Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacology, Biochemistry and Behavior. April 2002; 71(4): 533-54.
Ruppersberg JP. Intracellular regulation of inward rectifier K channels. European Journal of Applied Physiology. November 2000; 441: 1-11.
2002-2003 Journal Club Schedule