Current Topics in Pharmacology
12:30 PM, Wednesday, November 20, 2002
Room T-473 HSC
Speaker: Jennifer Wacker
Topic: Recent Developments in Gene Therapy for Parkinson's Disease
Deniz Kirik, Biljana Georgievska, Corinna Burger, Christian Winkler, Nicholas Muzyczka, Ronald J. Mandel, and Anders Bjorklund. Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer. Proceedings of the National Academy of Sciences USA. April 2002; 99(7): 4708-4713.
Jia Luo, Michael G. Kaplitt, Helen L. Fitzsimons, David S. Zuzga, Yuhong Liu, Michael L. Oshinsky, and Matthew J. During. Subthalamic GAD gene therapy in a Parkinson's disease rat model. Science. October 11, 2002; 298: 425-429.
Fabio Blandini, Giuseppe Nappi, Cristina Tassorelli and Emilia Martignoni. Functional changes of the basal ganglia circuitry in Parkinson's disease. Progress in Neurobiology. September 2000; 62(1): 63-88.
Ron Tintner and Joseph Jankovic. Treatment Options for Parkinson's Disease. Current Opinion in Neurology. August 2002; 15(4): 467-476.
Barkur S. Shastry. Parkinson disease: etiology, pathogenesis and the future of gene therapy. Neuroscience Research. 2001 September; 41(1): 5-12.
2002-2003 Journal Club Schedule