Current Topics in Pharmacology
12:30 PM, Wednesday, January 8, 2003
Room T-473 HSC
Speaker: William Catterall
Topic: Potassium Channel Gating: An Open and Shut Case
2002-2003 Journal Club Schedule
Declan A. Doyle, Joao Morais Cabral, Richard A. Pfuetzner, Anling Kuo, Jacqueline
M. Gulbis, Steven L. Cohen, Brian T. Chait, and Roderick MacKinnon. The structure of
the potassium channel: molecular basis of K+ conduction and selectivity. Science.
April 3 1998; 280: 69-77.
Maria A. Schumacher, Andre F. Rivard, Hans Peter Bachinger, and John P. Adelman.
Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/
calmodulin. Nature April 26, 2001; 410: 1120-1124.
Youxing Jiang, Alice Lee, Jiayun Chen, Martine Cadene, Brian T. Chait, and
Roderick MacKinnon. Crystal structure and mechanism of a calcium-gated potassium channel.
Nature. May 30, 2002; 417: 515-522.
Youxing Jiang, Alice Lee, Jiayun Chen, Martine Cadene, Brian T. Chait, and Roderick
MacKinnon. The open pore conformation of potassium channels. Nature. May 30, 2002;
Ofer Yifrach and Roderick MacKinnon. Energetics of pore opening in a voltage-gated
K+ channel. Cell. October 2002; 111: 231-239.