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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, January 8, 2003
Room T-473 HSC
Speaker: William Catterall
Topic: Potassium Channel Gating: An Open and Shut Case
References:
Declan A. Doyle, Joao Morais Cabral, Richard A. Pfuetzner, Anling Kuo, Jacqueline
M. Gulbis, Steven L. Cohen, Brian T. Chait, and Roderick MacKinnon. The structure of
the potassium channel: molecular basis of K+ conduction and selectivity. Science.
April 3 1998; 280: 69-77.
Maria A. Schumacher, Andre F. Rivard, Hans Peter Bachinger, and John P. Adelman.
Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/
calmodulin. Nature April 26, 2001; 410: 1120-1124.
Youxing Jiang, Alice Lee, Jiayun Chen, Martine Cadene, Brian T. Chait, and
Roderick MacKinnon. Crystal structure and mechanism of a calcium-gated potassium channel.
Nature. May 30, 2002; 417: 515-522.
Youxing Jiang, Alice Lee, Jiayun Chen, Martine Cadene, Brian T. Chait, and Roderick
MacKinnon. The open pore conformation of potassium channels. Nature. May 30, 2002;
417: 523-526.
Ofer Yifrach and Roderick MacKinnon. Energetics of pore opening in a voltage-gated
K+ channel. Cell. October 2002; 111: 231-239.
2002-2003 Journal Club Schedule
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