Pharmacology 514:
Current Topics in Pharmacology
Journal Club




Instructions for

JClub Archive

Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, January 29, 2003
Room T-473 HSC

Speaker: Danielle Ippolito
Topic: Cardiovascular Disease: Emerging Roles for Renegade Inflammation in Atherosclerosis


  1. David J. Fox, Jill Reckless, Stuart G. Warren, and David J. Grainger. Design, Synthesis, and Preliminary Pharmacological Evaluation of N-Acyl-3-aminoglutarimides as Broad-Spectrum Chemokine Inhibitors in Vitro and Anti-inflammatory Agents in Vivo. Journal of Medical Chemistry. January 17, 2002; 45(2): 360-70.

  2. Jill Reckless, Edward M. Rubin, Judy B. Verstuyft, James C. Metcalfe, and David J. Grainger. A Common Phenotype Associated with Atherogenesis in Diverse Mouse Models of Vascular Lipid Lesions. Journal of Vascular Research. May-June 2001; 38(3): 256-265.

  3. M. I. Cybulsky, K. Iiyama, H. Li, S. Zhu, M. Chen, M. Iiyama, V. Davis, J. C. Gutierrez-Ramos, P. W. Connelly, D. S. Milstone. A major role for VCAM-1, but not ICAM-1, in early atherosclerosis. Journal of Clinical Investigation May 2001; 107(10): 1255-62.

  4. Charles Q. Meng, Patricia K. Somers, Carolyn L. Rachita, Lisa A. Holt, Lee K. Hoong, X. Sharon Zheng, Jacob E. Simpson, Russell R. Hill, Lynda K. Olliff, Charles Kunsch et al. Novel phenolic antioxidants as multifunctional inhibitors of inducible VCAM-1 expression for use in atherosclerosis. Bioorganic & medicinal chemistry letters. September 16, 2002; 12(18): 2545-8.

  5. Cecil R. Pace-Asciak, Susan Hahn, Eleftherios P. Diamandis, George Soleas and David M. Goldberg. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease. Clinical Chimica acta. March 31, 1995; 235(2): 207-19.

  6. William B. Strawn, Mark C. Chappell, Richard H. Dean, Salah Kivlighn, and Carlos M. Ferrario. Inhibition of Early Atherogenesis by Losartan in Monkeys With Diet-Induced Hypercholesterolemia. Circulation. April 4, 2000; 101(3): 1586-1593.

  7. Daiana Weiss, John J. Kools, and W. Robert Taylor. Angiotensin II-Induced Hypertension Accelerates the Development of Atherosclerosis in ApoE-Deficient Mice. Circulation. January 23, 2001; 103(3): 448-454.

  8. Nanette Kass Wenger, Elizabeth Barrett-Connor, Peter Collins, Deborah Grady, Marcel Kornitzer, Lori Mosca, Andreas Sashegyi, Simin K. Baygani, Pamela W. Anderson, Elena Moscarelli and RUTH Investigators. Baseline characteristics of participants in the Raloxifene Use for The Heart (RUTH) trial. American journal of cardiology. December 1, 2002; 90(11): 1204-10.

  9. Brian W. Walsh, Sofia Paul, Robert A. Wild, Robert A. Dean, Russell P. Tracy, David A. Cox, and Pamela W. Anderson. The Effects of Hormone Replacement Therapy and Raloxifene on C-Reactive Protein and Homocysteine in Healthy Postmenopausal Women: A Randomized, Controlled Trial. Journal of clinical endocrinology & metabolism. January 2000; 85(1): 214-8.

  10. Adam F.M. Stone, Michael A. Mendall, Juan-Carlos Kaski, Tracey M. Edger, Paul Risley, Jan Poloniecki, A. John Camm, and Timothy C. Northfield. Effect of Treatment for Chlamydia pneumoniae and Helicobacter pylori on Markers of Inflammation and Cardiac Events in Patients With Acute Coronary Syndromes: South Thames Trial of Antibiotics in Myocardial Infarction and Unstable Angina (STAMINA). Circulation. September 3, 2002 106(10): 1219-1223.

  11. P. M. Ridker, N. Rifai, L. Rose, J. E. Buring, N. R. Cook. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. New England Journal of Medicine. November 14, 2002; 347(20): 1557-65.

  12. Gavin J. Blake, Robert J. Ostfeld, E. Kent Yucel, Nerea Varo, Uwe Schonbeck, Michael A. Blake, Marie Gerhard, Paul M. Ridker, Peter Libby, and Richard T. Lee. Soluble CD40 Ligand Levels Indicate Lipid Accumulation in Carotid Atheroma: An In Vivo Study With High-Resolution MRI. Arteriosclerosis, thrombosis, and vascular biology. January 1, 2003; 23(1): e11-e14.

  1. Peter Libby. Inflammation in atherosclerosis. Nature. December 2002; 420(6917): 868-74.

  2. Peter Libby, Paul M. Ridker, and Attilio Maseri. Inflammation and Atherosclerosis. Circulation. March 5, 2002 105(9): 1135-1143.

  3. Ernesto L. Schiffrin and (CIHR) Multidisciplinary Research Group on Hypertension. Beyond blood pressure: the endothelium and atherosclerosis progression. American journal of hypertension. October 2002; 15(10 Supplement 1): 115S-122S.

2002-2003 Journal Club Schedule

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