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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, March 31, 2004
Room T-473 HSC
Speaker: Jennifer Wacker
Topic: Recent Strategies to Prevent or Delay the Development of Prion Disease
References:
Mallucci G, Dickinson A, Linehan J, Klohn PC, Brandner S, Collinge J. Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science. 2003 Oct 31; 302(5646): 871-4.
White AR, Enever P, Tayebi M, Mushens R, Linehan J, Brandner S, Anstee D, Collinge J, Hawke S. Monoclonal antibodies inhibit prion replication and delay the development of prion disease. Nature. 2003 Mar 6; 422(6927): 80-3.
Reviews:
Aguzzi A, Polymenidou M. Mammalian prion biology: one century of evolving concepts. Cell. 2004 Jan 23; 116(2): 313-27.
Collinge J. Prion diseases of humans and animals: their causes and molecular basis. Annu Rev Neurosci. 2001; 24:519-50.
Weissmann C, Flechsig E. PrP knock-out and PrP transgenic mice in prion research. Br Med Bull. 2003; 66: 43-60.
2003-2004 Journal Club Schedule
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