Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, May 25, 2005
Room T-473 HSC


Speaker: Ben Major
Topic: The Transcriptional Signature of 'Good and Bad' Cancers Reconciles Two Different Models of How Metastatic Cancer Arises.

References:

  1. 1. Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordon-Cardo C, Guise TA, Massague J. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell. 2003 Jun; 3(6): 537-49.

  2. Minn AJ, Kang Y, Serganova I, Gupta GP, Giri DD, Doubrovin M, Ponomarev V, Gerald WL, Blasberg R, Massague J. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J Clin Invest. 2005 Jan; 115(1): 44-55.

  3. Van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R, Friend SH. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002 Jan 31; 415(6871): 530-6.

Reviews:
  1. 1. Hynes RO. Metastatic potential: generic predisposition of the primary tumor or rare, metastatic variants-or both? Cell. 2003 Jun 27; 113(7): 821-3. Review.

  2. Van't Veer LJ, Weigelt B. Road map to metastasis. Nat Med. 2003 Aug; 9(8): 999-1000.

  3. Friedl P, Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer. 2003 May; 3(5): 362-74. Review.


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