Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, October 12, 2005
Room T-473 HSC


Speaker: Nate Camp
Topic: Loss of polarity in epithelia and asymmetric cell division may promote cancer-in flies, that is.

References:

  1. Caussinus E, Gonzalez C. Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nat Genet. 2005 Oct;37(10):1125-9. Epub 2005 Sep 4.

  2. Bilder D, Li M, Perrimon N. Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science. 2000 Jul 7;289(5476):113-6.

  3. Bilder D, Perrimon N. Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature. 2000 Feb 10;403(6770):676-80.

Reviews:

  1. Bilder D. Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Dev. 2004 Aug 15;18(16):1909-25. Review.

  2. Clevers H. Stem cells, asymmetric division and cancer. Nat Genet. 2005 Oct;37(10):1027-8.

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