Pharmacology 514:
Current Topics in Pharmacology
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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, January 25, 2006
Room T-473 HSC


Speaker: Ning Zheng
Topic: Don't Know Much About Histones. Don't Know Much About Histone Variants.

References:

  1. Guillemette B, Bataille AR, Gevry N, Adam M, Blanchette M, Robert F, Gaudreau L. 2005 Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning. PLoS Biol 3(12):e384.

  2. Zhang H, Roberts DN, Cairns BR. 2005 Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss. Cell 123(2):219-31.

  3. Raisner RM, Hartley PD, Meneghini MD, Bao MZ, Liu CL, Schreiber SL, Rando OJ, Madhani HD. 2005. Histone variant H2A.Z marks the 5' ends of both active and inactive genes in euchromatin. Cell 123(2):233-48.

  4. Mizuguchi G, Shen X, Landry J, Wu WH, Sen S, Wu C. 2004. ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science 303(5656):343-8.

  5. Fan JY, Rangasamy D, Luger K, Tremethick DJ. 2004. H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding. Mol Cell. 16(4):655-61.

  6. Suto RK, Clarkson MJ, Tremethick DJ, Luger K. 2000. Crystal structure of a nucleosome core particle containing the variant histone H2A.Z. Nat Struct Biol. 7(12):1121-4.

Reviews:

  1. Lieb JD, Clarke ND. 2005. Control of Transcription through Intragenic Patterns of Nucleosome Composition. Cell. 123(7):1187-90.

  2. Kamakaka RT, Biggins S. 2005. Histone variants: deviants? Genes Dev. 19(3):295-310.

2005-2006 Journal Club Schedule
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