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Current Topics in Pharmacology
Phcol 514
12:30 PM, Wednesday, February 8, 2006
Room T-473 HSC
Speaker: Lisa Tsai
Topic: The Immune Police: Regulatory T cells in Autoimmune Type I Diabetes
References:
Nakayama B, Abiru N, Moriyama H, Babaya N, Liu E, Miao D, Yu L, Wegmann
DR, Hutton JC, Elliott JF, Eisenbarth GS. Prime role for an insulin epitope
in the development of type 1 diabetes in NOD mice. Nature. 2005 May
12;435(7039):220-3.
Tang Q, Adams JY, Tooley AJ, Bi M, Fife BT, Serra P, Santamaria P,
Locksley RM, Krummel MF, Bluestone JA. Visualizing regulatory T cell control
of autoimmune responses in nonobese diabetic mice. Nat Immunol. 2006
Jan;7(1):83-92.
Reviews:
Mathis D, Vence L, Benoist C. beta-Cell death during progression to
diabetes. Nature. 2001 Dec 13;414(6865):792-8. Review.
Piccirillo CA, Tritt M, Sgouroudis E, Albanese A, Pyzik M, Hay V. Control
of Type 1 Autoimmune Diabetes by Naturally Occurring CD4+CD25+ Regulatory T
Lymphocytes in Neonatal NOD Mice. Ann N Y Acad Sci. 2005 Jun;1051:72-87.
Goodnow CC, Sprent J, Fazekas de St Groth B, Vinuesa CG. Cellular and
genetic mechanisms of self tolerance and autoimmunity. Nature. 2005 Jun
2;435(7042):590-7. Review.
2005-2006 Journal Club Schedule
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